宋珏，副教授

研究方向：药物动力学、中药药理学、生物药剂学

电子邮箱：bao712@126.com

办公室：知行楼B座1215

教育经历：

(1) 2007/09至2012/06,安徽医科大学,药理学,博士

(2)2002/09至2005/06,中国药科大学,药理学,硕士

(3) 1997/09至2002/06,中国药科大学,药理学,学士

工作经历:

(1)2015/02至 今,安徽医科大学,新葡的京集团350vip8888官网药剂学教研室,副教授

(2)2008/07至2015/01,安徽医科大学,新葡的京集团350vip8888官网药剂学教研室,讲师

(3) 2005/07至2008/06,安徽医科大学,新葡的京集团350vip8888官网药剂学教研室,助教

科研项目:

(1)安徽省教育厅,安徽省高等学校科学研究项目重点科研项目, 2024AH050659,玉屏风影响磷脂代谢重编程调控 肺慢性炎症微环境中巨噬细胞极化的作用及机制研究, 2025-01至2026-12, 10万元,在研,主持

(2)国家自然科学基金委员会,青年科学基金项目, 81803868,药对“黄芪+白术”抗炎作用配伍增效的药 动学分子机制及与药物转运体SLC22As的相关性研究, 2019-01-01至2021-12-31, 21万元,结题,主持

发表论文情况:

1.Dalang Li, Chuanzong Qi, Jian Zhou, Zeqiang Wen, Xiangyu Zhu, Hongguang Xia and Jue Song.LPS-induced inflammation delays the transportation of ASP + due to down-regulation of OCTN1/2 in alveolar epithelial cells.Journal of Drug Targeting.Published online: Oct 2019. ISSN1061-186X. 2020, 28( 4):437-447. (IF:5.123)

2.Chuanzong Qi, Jian Zhou, Zihao Wang, Xin Fang, Dalang Li, Yong Jin, Jue Song*.  Cigarette smoke extract combined with lipopolysaccharide reduces OCTN1/2 expression in human alveolar epithelial cells in vitro and rat lung in vivo under inflammatory conditions. International Immunopharmacology.2020. https://doi.org/10.1016/j.intimp.2020.106812 (IF: 4.932)

3.Jian Zhou, Chuanzong Qi, Xin Fang, Zihao Wang, Shuyi Zhang, Dalang Li, Jue Song. DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS. Life Sciences, 276 (2021) :119089. doi: 10.1016/j.lfs.2021.119089 (IF:6.780 )

4.Xin Fang, Shuyi Zhang, Zihao Wang, Jian Zhou, Chuanzong Qi, Jue Song. Cigarette smoke extract combined with LPS down-regulates the expression of MRP2 in chronic pulmonary inflammation may be related to FXR. Molecular Immunology, 137 (2021) :174–186.   (IF:4.562)

5.Xin Fang, Zihao Wang, Chuanzong Qi, Jian Zhou a,b , Shuyi Zhang and Jue Song. The changes of MRP2 expression in three kinds of pulmonary inflammation models: the downregulation occurred in cigarette smoke extract (CSE) stimulation group and CSE plus LPS stimulation group, unchanged in LPS stimulation group. Toxicology Mechanisms And Methods, 2021, 31(6):413-424 . (IF: 2.885)

6.Zihao Wang,Xin Fang,Shuyi Zhang,Jue Song.Pulmonary inflammation caused by cigarette smoke combined with lipopolysaccharide up-regulated OATP2B1 in rat lung tissue and pulmonary epithelial cells. Experimental Lung Research. 2022, 48(3):114-125. (IF: 1.7)

7.Shuyi Zhang, Xianwang Lu, Xin Fang, Zihao Wang, Shihao Cheng, Jue Song. Cigarette smoke extract combined with LPS reduces ABCA3 expression in chronic pulmonary inflammation may be related to PPARγ/ P38 MAPK signaling pathway. Ecotoxicology and Environmental Safety.2022, 244:114086 (IF: 6.8)

8.闻泽强，李大朗，宋珏.玉屏风水煎剂及其组分对大鼠肾脏组织及HEK-293细胞OATl/3表达的影响.中成药. 2020, 42(6): 1457-1462.